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Ketamine Treatment Makes National News

Here is a collection of stories and articles from the media that highlight ketamine therapy.

Ketamine Isn’t an Opioid and Treats Depression in a Unique Way
Johns Hopkins University School of MedicineJuly 31, 2019
Ketamine has gotten a bad rap as an opioid when there’s plenty of evidence suggesting it isn’t one, Johns Hopkins experts say.

Ketamine May Relieve Depression By Repairing Damaged Brain Circuits
NPR, April 11, 2019
The anesthetic ketamine can relieve depression in hours and keep it at bay for a week or more.

Special K: Ketamine, From Party Drug To Depression Medication
NPR, April 22, 2019
Recently, the FDA approved a new drug based on ketamine to treat treatment-resistant depression.

Ketamine offers a lifeline for people with severe depression, suicidal thoughts
CNN, August 4, 2018
Ketamine is a powerful medication used in hospitals primarily as an anesthetic, but recent scientific studies have shown significant promise with treatment-resistant depression and suicidal ideation.

Can We Stop Suicides?
New York Times, November 30, 2018
It’s been way too long since there was a new class of drugs to treat depression. Ketamine might be the solution.

Lasers Highlight Ketamine’s depression-fighting Secrets
WIREDmagazine, April 11, 2019
Researchers implanted prisms in mouse brains to watch how ketamine affects neurons. The findings could lead to more effective antidepressant treatments.


Intramuscular Ketamine Injections

Ketamine Infusions VS. Intramuscular Ketamine Injections

If you have been researching ketamine therapy at all in the last few months, you may have come across ads from clinics offering “intramuscular ketamine injections.” It is being advertised as the “more affordable” ketamine therapy. Recently, I asked Dr. Coakley our Medical Director why she chooses IV ketamine over the IM injections.

Ketamine can be administered in several forms, many of which have differing levels of effectiveness. Oral preparations typically are less effective as they must be processed by the digestive system. Sublingual (dissolved under the tongue) is also less effective but still immensely helpful for selected patients. Intramuscular administration has shown similar rates of effectiveness to IV infusion. The differences between the two methods can be summed up below:

1. IV infusion typically requires one needle stick to start the IV, intramuscular may require multiple injections per treatment session.

2. IV infusion can be increased, decreased, or stopped depending on the patient’s response during the treatment. Intramuscular administration cannot be adjusted or “taken back” after injection.

3. Many patients have found that IV infusions seem to maintain symptom relief for longer periods between treatments. The result is that patients having intramuscular treatment may require more frequent treatments.

4. The rate of onset and recovery is also different, leading to an intense onset (which can be uncomfortable for some patients) and slower recovery with intramuscular injection versus IV infusion. Again, with intramuscular injection, it is not possible to stop the administration, therefore you must mitigate any adverse side effects through reassurance and sometimes other medications to counteract the side effects and allow the medication to “run its course.”

5. Both forms of administration require supervision by a licensed, prescribing provider and should only be given by a practitioner specifically trained in the use of ketamine. Monitoring of your vital signs throughout your treatment is also paramount to ensuring patient safety.

Still, have questions about ketamine therapy? Feel free to call our office, we can help come up with a care plan that works for you!



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